Role of VEGF-C in metastasis of non-small cell lung cancer
10.3760/cma.j.issn.1006-9801.2010.09.028
- VernacularTitle:血管内皮生长因子C在非小细胞肺癌转移中的作用
- Author:
Xiujun SONG
- Publication Type:Journal Article
- Keywords:
Vascular endothelial growth factor C;
Carcinoma,non-small-cell lung;
Neoplasm metastasis
- From:
Cancer Research and Clinic
2010;22(9):647-648
- CountryChina
- Language:Chinese
-
Abstract:
Vascular endothelial growth factor-C (VEGF-C) can promote the growth of tumor thymphangiogenesis by binding with receptor VEGFR-2 and VEGFR-3. It is an important factor of tumor lymphatic metastasis. Lymphatic metastasis is the major diffusion way for non-small cell lung cancer(NSCLC).The over expression of VEGF-C is significantly correlated to metastasis and prognosis of NSCLC. This article rewiews the bionomics and the functions of VEGF-C in metastasis of NSCLC.
