The diagnosis value of a new tumor marker CK18-3A9 serum level for gastric cancer

VernacularTitle:新型肿瘤标志物CK18-3A9血清水平对胃癌诊断的价值
Author: Hongyan ZHANG ; Zhiling JIA ; Feng LIANG ; Chang LIU
Publication Type:Journal Article
Keywords: Stomach neoplasms; Keratin-18; CA72-4
From: Cancer Research and Clinic 2010;22(11):733-735
CountryChina
Language:Chinese
Abstract: Objective To investigate the diagnosis value of a new tumor marker CK18-3A9 in gastric cancer patients. Methods The serum level of CK18-3A9 in 350 gastric cancer patients, 150 gastritis patients and 500 healthy controls was detected with chemoluminescence, the diagnosis efficacy between the serum CK18-3A9 and CA72-4 was compared. Results The sensitivity, specificity of CK18-3A9 were 46.29 % and 96.92 %, but the sensitivity, specificity of CA72-4 were 26.00 % and 93.23 %, respectively. The differences were significant (P ＜0.001). Conclusion The serum level of CK18-3A9 maybe a new auxiliary diagnosis marker for gastric cancer.