Prevalence of chronic kidney diseases and associated factors on the basis of stratified random sampling among elderly people in two districts of Jiangsu province, China
10.3760/cma.j.issn.1001-7097.2010.11.002
- VernacularTitle:江苏两个地区老年人群慢性肾脏病的分层随机抽样调查
- Author:
Yanbei SUN
;
Hong LIU
;
Ming WU
;
Yanli WANG
;
Jingzhi WU
;
Weixin SUN
;
Jinfang YANG
;
Bicheng LIU
- Publication Type:Journal Article
- Keywords:
Kidney disease,chronic;
Epidemiology;
Prevalence;
Elderly
- From:
Chinese Journal of Nephrology
2010;26(11):812-817
- CountryChina
- Language:Chinese
-
Abstract:
Objective To survey the epidemiology of chronic kidney disease (CKD) among elderly people in two districts of Jiangsu province, China. Methods A total of 1404 residents aged 60 years or older in Huaian and Suzhou city in Jiangsu province were randomly recruited from the community population. All the people were screened for albuminuria (increased morning spot urine albumin-to-creatinine ratio, UACR) and reduced renal function (decreased eGFR by simplified MDRD equation). Urinary creatinine and albumin, serum creatinine, uric acid, cholesterol,triglyceride, low density lipoprotein-cholesterol, high-density lipoprotein cholesterol and fasting blood (1.73 m2) -1] and/or albuminuria (UACR ≥30 mg/g). The associations between healthy characteristics and indicators of kidney damage were examined. Results A total of 1316 (93.7%) elderly people completed the study. The prevalence of CKD was 32.3% and the awareness rate was only 9.6%. Albuminuria and reduced renal function were found in 30.2% and 3.2% of subjects respectively. The Logistic regression model showed that age, gender, hypertension,hypercholesterinemia and hyperuricaemia were independently associated with CKD. Systolic blood pressure (SBP) of 140-159 mm Hg exhibited a lower adjusted OR value (0.675) for CKD, while SBP of 160-179 mm Hg and of at least 180 mm Hg exhibited higher adjusted OR values (1.330 and 1.146). Similarly, FBG of 5.6-6.9 mmol/L exhibited a lower adjusted OR value for CKD as compared to FBG of at least 7.0 mmol/L (0.628 vs 1.941). Conclusions The prevalence of CKD in elderly people of Jiangsu province is quite high. Age, gender, hypertension,hypercholesterinemia and hyperuricaemia are independent risk factors for the development of CKD.
