Treatment of infantile hemangioma in parotid gland region with pingyangmycin injection

Jinsong HOU; Haikuo TANG; Qian TAO; Haichao LIU; Xiaolin WU; Guiqing LIAO; Xiaoping YANG; Hongzhang HUANG

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Treatment of infantile hemangioma in parotid gland region with pingyangmycin injection

VernacularTitle:平阳霉素治疗婴幼儿腮腺咬肌区血管瘤
Author: Jinsong HOU ; Haikuo TANG ; Qian TAO ; Haichao LIU ; Xiaolin WU ; Guiqing LIAO ; Xiaoping YANG ; Hongzhang HUANG
Publication Type:Journal Article
Keywords: Infant; Parotid gland region; Hemangioma; Pingyangmycin (PYM); Treatment
From: Chinese Journal of Medical Aesthetics and Cosmetology 2010;16(6):370-372
CountryChina
Language:Chinese
Abstract: Objective To evaluate the clinical efficacy of pingyangmycin (PYM) injection on infantile hemangioma located in the parotid gland region. Methods Twelve patients were treated by intralesional injection of PYM. When necessary, the injections were repeated at an interval of one week, but not more than 3-4 sessions within a therapeutic period. Normally, the secondary therapeutic period was performed 1 month later. The general and local adverse responses were recorded and the clinical outcomes were assessed with a follow-up of 1 to 3 years. Results Complete clinical resolutions were achieved in 10 patients. 2 patients received one injection, 3 patients received 2 injections, 3 patients received 3 injections, and 2 patients received 4 injections. The remaining 2 patients with partial resolution received 6 and 7 injections respectively. No clinical recurrence was observed during the follow-up of 1 to 3 years. No ulcerations or postoperative sears in injection regions were presented. The function of facial nerve was remained normality in all patients. The systematic side effects included transient pyrexia and poor appetite appeared in partial patients. No allergy cases were found. Conclusion Treatment of infantile hemangioma located in parotid gland region with PYM injection reveals a high rate of complete clinical resolution, with fair cosmetic results and short treatment time, and it does not damage the facial nerve or form local scar.The treatment time of PYM injection seems to be positively related to size of the lesions.