Relationship between circulating endothelial cells and tumor angiogenesis
10.3760/cma.j.issn.1006-9801.2010.03.022
- VernacularTitle:循环内皮细胞与肿瘤血管生成的关系
- Author:
Xiao HAN
;
Zhehai WANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Circulating endothelial cells;
Neovascularization,pathologic
- From:
Cancer Research and Clinic
2010;22(3):211-213
- CountryChina
- Language:Chinese
-
Abstract:
Circulating endothelial cells (CEC) are endothelial cells which are detected in the peripheral blood. There are very few CEC in healthy adults while the number is obviously increasing in patients with arthrosclerosis, diabetes mellitus, lupus erythematosus, et al. Nowadays, flow cytometry analysis and immunomagnetic isolation for CEC are employed successfully in clinic and scientific research. Several research findings have confirmed that there is intimate relation between CEC and tumorigenesis. Because of the important role in angiogenesis and tumor growth, CEC would be a perspective tumor marker in antiangiogenesis and would also predict the chemotherapy efficacy.
