The effect of pulsed electromagnetic fields on the biomechanical properties of the femur in ovariectomized rats
10.3760/cma.j.issn.0254-1424.2010.12.004
- VernacularTitle:不同强度脉冲电磁场对去势大鼠股骨生物力学特性的影响
- Author:
Deng XIAO
;
Chengqi HE
;
Hongchen HE
- Publication Type:Journal Article
- Keywords:
Pulsed electromagnetic fields;
Magnetic field intensity;
Ovariectomized rats;
Biomechanical properties
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2010;32(12):898-901
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of pulsed electromagnetic fields (PEMFs) of different intensities on the biomechanical properties of the femur in ovariectomized rats so as to determine the intensity for the best therapeutic efficacy. Methods Fifty female Sprague-Dawley rats were randomly divided into (1) a sham-operated control group (no PEMF treatment) , (2) ovariectomized control group (no PEMF treatment) (3) ovariectomized group Ⅰ (PEMF treatment at 8 Hz and 0.77 mT intensity, 40 min daily for 30 days) (4) ovariectomized group Ⅱ (PEMF treatment at 8 Hz and 3.82 mT intensity, 40 min daily for 30 days) and (5) ovariectomized group Ⅲ( PEMF treatment at 8 Hz and 9.87 mT intensity, 40 min daily for 30 days). Except for the 10 rats of the sham-operated control group, all the others received a standard ovariectomy. Serum estradiol (E2) and the biomechanical properties of one femur (peak load, maximum displacement, maximum energy absorption, maximum stress, maximum strain and modulus of elasticity) were assessed after 30 days of PEMF treatment. Results In group Ⅱ the biomechanical properties of the femur were significantly better than in group Ⅰ or the ovariectomized control group. In groups Ⅰ and Ⅲ the biomechanical properties of the femur were not significantly better than in the sham-operated group. In group Ⅱ the biomechanical properties of the femur were significantly better than in groups Ⅰ or Ⅲ. Conclusion PEMFs at 3.82 mT can improve the biomechanical properties of the femur significantly.
