Central arterial augmentation index in Uygur health adults from Hetian,Xinjiang Detection by Sphygmocor pulse wave analysis system
10.3969/j.issn.1673-8225.2010.52.047
- VernacularTitle:Sphygmocor脉搏波分析系统检测新疆和田维吾尔族正常人群中心动脉反射波增强指数
- Author:
Xiaohui LIANG
;
Xinjuan XU
;
Yanping MA
;
Lihua SUN
;
Yitong MA
;
Ding HUANG
;
Yining YANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2010;14(52):9877-9880
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Arterial stiffness is an independent risk factor for cardiovascular disease.Augmentation index(Alx)is an important marker which reflects the systemic arterial stiffness.OBJECTIVE:To investigate Alx and the affecting factors in Xinjiang Uygur health adults.METHODS:A total of 559 healthy adults(251 males and 308 females)with a mean age of(44.95±11.87)years were selected from Hetian,Xinjiang Uygur Autonomous Region.The following indexes of all subjects were measured,including questionnaire,physical examination,blood biochemistry and C-reactive protein(CRP).Central systolic blood pressure(cSBP)and central Alx were measured by Sphygmocor.Pearson correlation and partial correlation analysis were used for two-group analysis of correlation,and multiple regression analysis was used to analyze influential factors for Alx.RESULTS AND CONCULUSION:Alx was greater in female than in male and was positively related to age in both sexes(male:r=0.548,female:r =0.405,P < 0.05),as well as adjusted other influential factors(male:r=0.182,female:r =0.234,P < 0.05).Multiple regression analysis showed that cSBP,systolic blood pressure(SBP),sex,age and CRP were main factors which affected Alx in Uygur healthy adults,cSBP,SBP,age,body mass and CRP were main factors which affected Alx in the male,while cSBP,SBP,age,height and CRP were main factors which affected Alx in the female.Results revealed that Alx was greater in female than in male which was positively related to age in both sexes.Age,cSBP,SBP and CRP were main factors that affected Alx in Xinjiang Uygur healthy adults.
