A case of grideofulvin-induced phototoxic reaction.
- Author:
Jin Soo KANG
;
Tae Heung KIM
;
Ki Beom PARK
- Publication Type:Original Article
- Keywords:
Griseofulvin;
Phototoxic reaction
- MeSH:
Eating;
Female;
Griseofulvin;
Humans;
Middle Aged;
Petrolatum;
Skin
- From:Korean Journal of Dermatology
1992;30(4):524-528
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of a phototoxic reaction in a 48-year-old female induced by griseofulvin ingestion. The patient hac! erythematous papules, vesicles and patches on the sun-exposed areas. Phototest revealed a decreased minimal erythemal dose to UVA (10J/cm). Photopatch tests with 1%, 5%, 10% Griseofulvin ointment and vaseline as a control and photoingestion tests with Griseofulvin (50mg b.i.d.) were all negative. After the cessation of Griseofulvin, her skin lesions were markedly improved with complete loss of photosensitivity.