Factors contributing to myasthenic crisis after thymectomy-a multivariate analysis study

VernacularTitle:重症肌无力病人胸腺切除术后危象发生的多因素分析
Author: Jinshan MA ; Xiaolei WANG ; Kang CHEN ; Erlan NU ; Xianfeng LI ; Kaiti XIAO ; Yongwei YANG ; Chengyü JIN ; Rui GUO
Publication Type:Journal Article
Keywords: Myasthenia gravis; Thymectomy; Risk factors
From: Chinese Journal of Thoracic and Cardiovascular Surgery 2011;27(1):27-29
CountryChina
Language:Chinese
Abstract: Objective To evaluate the risk factors of myasthenic crisis(MC) after thymectomy for myasthenia gravis (MG) Methods A retrospective study was conducted in 84 patients with MG from July 1995 to December 2009. The following factors were evaluated: sex, age, history of preoperative myasthenic crisis, Osssrmen classification, use steroid hormones and anticholinesterase drugs before operation, operation methods, operation time, thymoma, pathology, transfusion, course of disease, postopertive lung infection,etc. Multivariate logistic regrossion analysis was used to find the predictors of postoperative myasthenic crisis. Results Twenty-four patients(28.6%) developed myasthenic crisis after thymectomy. Statistics showed that history of preoperative myasthenic crisis, Ossermen classification, operation methods, operation time were related to postoperative myasthenic crisis. Conclusion Preoperative myastheric crisis, Ossermen classification≥I b, traditional operation methods, long opertion time are the independent risk factors for myasthenic crisis after thymectomy.