Evaluation of Anesthetic Effects of Enflurane by Spectrum Analysis of Rat EEG.
10.4097/kjae.1992.25.4.648
- Author:
Mann Gee LEE
1
;
Woon Yi BAEK
;
Byung Kwon KIM
;
Choong Young KIM
Author Information
1. Department of Pharmacology, School of Medicine, Kyungpook National University, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
Enflurane;
EEG;
Spectrum analysis;
Rat
- MeSH:
Anesthesia;
Anesthetics*;
Animals;
Electroencephalography*;
Enflurane*;
Inhalation;
Rats*;
Scalp;
Spectrum Analysis*
- From:Korean Journal of Anesthesiology
1992;25(4):648-655
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To evaluate the depth of enflurane anesthesia, spectrum analysis of rat EEG was used. Bipolar EEG was recorded through one lead form rat scalp during inhalation with 1,2,3 and 4% of enflurane, and analysed to produce the spectrum from which the density of each band(delta 1-3.25Hz, theta 3.5-7.75Hz, alpha 8-12.75Hz, beta2 18-20.75Hz, and beta3 21-31.75Hz)and total density, and medican power frequency were calculated. Differences among the EEG patterns, which were represented by F values through discriminant analysis of those 8 variables, in each level of anesthesia were significant among all concentrations except between 1% and 2% enflurane administration. The results suggest that the discriminat anlysis for the EEG parameters derived from power spectrum analysis can apply to determine the level of enflurane anesthesia.
