Sulfur-containing amides from Entada phaseoloides.
- Author:
Hui XIONG
;
Er XIAO
;
Yinghong ZHAO
;
Guangzhong YANG
;
Zhinan MEI
- Publication Type:Journal Article
- From:
Acta Pharmaceutica Sinica
2010;45(5):624-6
- CountryChina
- Language:English
-
Abstract:
To study the chemical constituents of the Entada phaseoloides (L.) Merr., seeds of Entada phaseoloides were extracted with 70% ethanol at room temperature. Isolation and purification were performed by silica gel, reversed-phase silica gel column chromatography and semi-preparative HPLC. Structures of the pure compounds were established on the basis of spectral analysis. Four sulfur-containing amide compounds were isolated from the n-BuOH-soluble fraction and identified as entadamide A-beta-D-glucopyranosyl-(1-->3)-beta-D-glucopyranoside (1), entadamide A (2), entadamide A-beta-D-glucopyranoside (3) and clinacoside C (4). Compound 1 is a new compound. Compound 4 is isolated from the genus Entada for the first time.
