Fingerprints of Tongmai Keli by HPLC-DAD-MS.
- Author:
Beijia LI
;
Cheng XIANG
;
Xiuwei YANG
;
Lijun WU
;
Dean GUO
;
Min YE
- Publication Type:Journal Article
- From:
Acta Pharmaceutica Sinica
2010;45(11):1410-4
- CountryChina
- Language:Chinese
-
Abstract:
In order to clarify the chemical composition of Tongmai Keli, a HPLC fingerprint was established, and the 22 peaks were characterized by LC-DAD-MS. The herbal sources of these peaks were assigned. The results implied that genistin 8-C-glucoside, puerarin, daidzein 8-C-apiosyl (1, 6)-O-glucoside, daidzin, and salvianolic acid B were the main constituents of in Tongmai Keli. Ten batches of Tongmai Keli produced by different pharmaceutical companies were analyzed. Although different batches contained similar compounds, the contents of major compounds were significantly different. The method established in this study could be used for the quality control of Tongmai Keli.
