Beneficial effects of droxicainide on ventricular fibrillation and infarct size after coronary occlusion
- VernacularTitle:Droxicainide对冠脉阻塞后心室纤颤及梗塞面积方面的有利作用
- Author:
Anyun SHI
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Perfusion
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of droxicainide was investigated in a rabbit model of myocardial ischemia and reperfusion. The rabbits were randomized to either a saline-treated control group (n=18) or a droxieainide-treated group (n=11). In the control group, the incidence of ventricular fibrillation after coronary ligation was 14/18 (77.7%) and nine died (64.3%). Ventricular fibrillation occurred in eight (72.7%) droxieainide treated rabbits, but all reverted spontaneously (P
