Confocal laser endomicroscopy in diagnosis of histological gastritis
- VernacularTitle:共聚焦激光显微内镜对组织学胃炎的诊断
- Author:
Jianna ZHANG
;
Tao YU
;
Yanqing LI
;
Yuting GUO
;
Hong HU
;
Tingguo ZHANG
- Publication Type:Journal Article
- Keywords:
Microscopy,confocal;
Gastroscopy;
Gastritis
- From:
Chinese Journal of Digestive Endoscopy
2008;25(7):347-352
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the diagnostic value of confoeal laser endomicroscopy(CLE) in histological gastritis.Methods A total of 149 patients underwent CLE.Standard locations and focal lesions were examined by confocal imaging, and specimens were taken by targeted biopsy.The relationship between confocal images and histological findings were studied systemically.Results The sensitivity,specificity and accuracy of CLE in diagnosis of atrophy were 83.6%,99.6%and 97.5%,respectively;and those in moderate to severe neutrophil infiltration were 81.9%,99.3%,and 95.8%,respectively.The mean kappa values for inter-and intra-observer agreement on the classification of confocal images in groups were 0.749 and 0.811 respectively.Conclusion The validity and reproducibility of CLE in diagnosis of histologic gastritis are promising,which might warrant its further application in clinical practice.
