The Anti-fatigue Effect of Complex Bear Gall Agent in Mice
10.3760/cma.j.issn.1008-6706.2010.24.014
- VernacularTitle:复方熊胆制剂抗疲劳作用研究
- Author:
Fengguo ZHAI
;
Yuegang CHAO
;
Shijie YANG
- Publication Type:Journal Article
- Keywords:
Complex bear gall agent;
Anti-fatigue;
Hepatic glycogen;
Lactic acid;
Lactate dehydrogenase
- From:
Chinese Journal of Primary Medicine and Pharmacy
2010;17(24):3342-3344
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the anti-fatigue effect of complex bear gall agent in mice.Methods Different dose of complex bear gall agent(4.4ml/kg、6.6ml/kg、13.2rml/kg)were given to mice by intragastric administration. The time of climbing-pole and loaded-swimming, hepatic glycogen content, serum urea nitrogen,lactic acid and lactate dehydrogenase of mice after swim were observed. Results The experiments indicated that complex bear gall agent could greatly increase the time of loaded-swimming and climbing Pole,increase the hepatic glycogen content and serum lactate dehydrogenase activity ,decrease serum urea nitrogen and blood lactic acid content in mice. Conclusion Complex bear gall agent had a significant anti-fatigue effect.
