Research status in relationship between Survivin and lung cancer
- VernacularTitle:凋亡抑制基因Survivin与肺癌的关系
- Author:
Sheng YANG
;
Huishan LU
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Inhibitor of apoptosis proteins;
Survivin
- From:
Cancer Research and Clinic
2008;20(9):641-643
- CountryChina
- Language:Chinese
-
Abstract:
Survivin is a recently identified member of the inhibitor of apoptosis protein (IAP) family which is a multifunctional protein with inhibition of apoptosis and regulation of cell division, and other functions. It is highly expressed in transformed cell lines and in a large number of malignancies, but undetectable in terminally differentiated adult tissues. Survivin play an important role in tumorigenesis of lung cancer. On the basis of these findings, Survivin will be of great interest as both a diagnostic tumor marker and as a potential suitable target for anti-lung cancer therapies.
