Transcriptional analysis of Brucella virulence regulation genes under stress conditions and during cell infection
- VernacularTitle:布鲁菌重要毒力调控基因在环境刺激和细胞侵染过程中的转录研究
- Author:
Yufei WANG
;
Feng QIAO
;
Zhijun ZHONG
;
Zhoujia WANG
;
Xinying DU
;
Yaqin YU
;
Zeliang CHEN
;
Liyu HUANG
- Publication Type:Journal Article
- Keywords:
Brucella;
Transcription;
Gene expression
- From:
Chinese Journal of Microbiology and Immunology
2008;28(10):919-924
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the important virulence regulation genes of Brucella,and to understand their function.Methods Quantitative RT-PCR was used to quantify their relative transcription profiles under stress conditions and during macrophage cell infection.Results These genes were activated at different levels under these conditions and during cell infection,indicating their roles in pathogenesis at different srage of infection.Conclusion The transcription profiles of these genes have different effects about their functions.
