A prospective study of the cognitive changes of type 2 diabetes mellitus patients complicated with stroke
- VernacularTitle:2型糖尿病患者合并脑卒中后认知功能改变的前瞻性研究
- Author:
Yue WANG
;
Xiaoyun XU
;
Gang LI
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus;
Stroke;
Cognitive function
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2008;30(10):697-699
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of cognitive changes in type 2 diabetes mellitus pa-tients complicated with stroke. Methods One hundred and one stroke patients were recruited and allocated to thetype 2 diabetes mellitus group (34 patients) and sixty-seven patients in the control group (67 patients) according tobeing with or without type 2 diabetes mellitus. All the patients were evaluated, after 3 weeks, 6 months and 12months of onset of stroke, with regard to their cognitive functions by using the Mini-mental State Examination(MMSE) and Montreal Cognitive Assessment (MOCA). Results Average scores obtained in MMSE and MOCAtests were significantly lower at 3 weeks and 6 months after onset in the type 2 diabetes mellitus group when comparingwith control group. In the type 2 diabetes mellitus group, no significant difference was observed between 3 weeks and6 months after onset of stroke with regard to scores of MMSE and MOCA ( P > 0.05 ), however, the score at 6 monthswas significantly lower than that at 12 months after onset (P <0.05). On the other hand, scores of MMSE (P >0.05 ) and MOCA (P > 0.05 ) in the control group were not any statistically different among various time points ofobservation. Conclusion Type 2 diabetes mellitus will aggravate cognitive dysfunctions of stroke patients, whichstarted to recover in 6 months of onset of the stroke.
