Long-term survival rate of precancerous lesions and early esophageal cancers after endoscopic mucosal resection
- VernacularTitle:内镜下黏膜切除术治疗早期食管癌和癌前病变长期生存率观察
- Author:
Guoqing WANG
;
Changqing HAO
;
Wenqiang WEI
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Precancerous conditious;
Endoscopic mucosal resection
- From:
Chinese Journal of Digestive Endoscopy
2008;25(11):584-586
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the long-term survival rate of precancerous lesions and early esophageal cancer after endoscopic mucosal resection (EMR).MethodsThe follow-up endoscopy was performed in 154 patients with early esophageal cancer and precancerous lesions who underwent EMR.The examinations were carried out at 1 month,6 months and every 1 year after the procedure,respectively,and argon plasma coagulation (APC) was applied if a recurrent lesion was suspected.The follow-up rate was 100%.ResultsAfter EMR,reecurence occurred in 6 cases (3.9%) in 5 years,of which 4 received esophagectmy,1 underwent APC,and the other one died from matastasis.The 5-year survival rate was 97.4% (150/154),with 1 died from matastasis and 3 from noncancerous diseases.The 5-year survival rate of 125 patients with high grade dysplasia,carcinoma in situ and intramucosal carcinoma was 97.6%( 122/ 125),with 1 died from noncancerous disease and 1 from metastasis.The 5-year survival rate of 29 patients with low grade dysplasia was 96.6% ( 28/29 ) with 1 patient died from noncancerous disease.ConclusionEMR,as a minimally invasive procedure,is suitable for precancerous lesions and early esophageal cancer,especially for high grade dysplasia,carcinoma in situ and intramueosal carcinoma,with little sequela and long-term survival.
