fMRI study of brain of stroke patients during knee extension-flexion of the affected side
- VernacularTitle:脑卒中后偏瘫侧膝关节屈伸的脑功能性磁共振成像研究
- Author:
Junfa WU
;
Yi WU
;
Yongshan HU
;
Luchun JIANG
;
Shuyong LIU
;
Hanqiu LIU
- Publication Type:Journal Article
- Keywords:
Stroke;
Knee flexion-extension;
Functional magnetic resonance imaging
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2008;30(11):756-759
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the underlying mechanism of motor recovery of the hemiplegic lower extremity in stroke patients. Methods The brain activation pattern during sequential extension-flexion of the affect-ed knee of 7 stroke patients and 8 healthy subjects was observed by blood-oxygen- level-dependent fMRI (BOLD-fM-RI) and analyzed by microsoft SPM5. Results When executing unilateral knee flexion-extension, contralateral paracentral lobe and contralateral supplementary motor area and right temporal gyms and inferior parietal lobes of both sides were significantly activated in all the healthy subjects, while the ipsilateral parietal lobe BA7 and BA5 were sig-nificantly activated in 6 of the 7 stroke patients. Conclusions Sequential extension-flexion of the affected knee of stroke patients was probably dependent on the activation of BA7 and BA5 in the intact side. Compensatory activation of the intact hemisphere might be one of the main mechanisms for the paretic lower extremity motor recovery in stroke patients.
