Progress in pathogenic secretome research
10.3760/cma.j.issn.1673-4408.2011.01.007
- VernacularTitle:病原体分泌蛋白质组的研究进展
- Author:
Shuxian LI
;
Dan XU
- Publication Type:Journal Article
- Keywords:
Secreted protein;
Secretome;
Pathogen;
Proteomics
- From:
International Journal of Pediatrics
2011;38(1):18-21
- CountryChina
- Language:Chinese
-
Abstract:
Secretome includes all the gene products secreted by a cell. The development of proteomicbased approaches and genome-based computational prediction technology have gradually revealed secretome plays an important role in pathogen infection recently. Secretome facilitates pathogen to proliferate and invade the host by inhibiting the host's immune system, resisting acidic PH conditions, snatching nutrition and so on.Identification of pathogenic secretome helps discovering new drug targets and biomarkers, and supporting the diagnosis and treatment.
