Progress of rotavirus infection and NF-κB
10.3760/cma.j.issn.1673-4408.2011.01.008
- VernacularTitle:轮状病毒感染与NF-κB相关性的研究进展
- Author:
Manli YU
- Publication Type:Journal Article
- Keywords:
Rotavirus infection;
NF-κB
- From:
International Journal of Pediatrics
2011;38(1):21-23
- CountryChina
- Language:Chinese
-
Abstract:
In rotavirus infection, NF-κB plays an important role in regulation of host defense and pathogenic of rotavirus. On the one hand, by the signal regulation mechanism of NF-κ Bmediated, host plays antiviral effect and immune-related role. On the other hand, by blocking NF-κB nuclear accumulation and other reactions, rotavirus evades the host immune response. Consequently, the outcome of rotavirus infection may depend on dominant way of NF-κ Bregulating.
