Renal lesion associated with Schimke immuno-osseous dysplasia: a case report and review of the literature
10.3760/cma.j.issn.1001-7097.2009.02.006
- VernacularTitle:Schimke免疫-骨发育不良肾损害一例暨文献复习
- Author:
Wenfang CHEN
;
Xueqing YU
;
Shicong YANG
;
Weiming GUAN
;
Wenxing PENG
;
Yu DONG
;
Jinlang WU
- Publication Type:Journal Article
- Keywords:
Glomerulosclerosis,focal;
Nephrotic syndrome;
Developmental disabilities;
Schimke immuno-osseous dysplasia
- From:
Chinese Journal of Nephrology
2009;25(2):97-100
- CountryChina
- Language:Chinese
-
Abstract:
Objective To report a Chinese boy suffering from nephrotic syndrome associated with Schimke immuno-osseous dysplasia (SIOD). Methods The clnical data and pathological changes of renal biopsy were analyzed and associated literatures were reviewed. The clinicopathological features and diagnosis of SIOD were discussed. Results The first symptom of the patient was recurrent infections. Growth retardation, spondyloepiphyseal dysplasia accompanied by nephrotic syndrome and defective cellular immunity were seen as clinical features in this patient. Renal pathology showed focal segmental glomerulosclerosis. Conclusion Combining the clinical manifestation with renal pathology, the case is diagnosed as Schimke immuno-osseous dysplasia.
