The rehabilitating effect of hyperbaric oxygen on visual pathway lesions
10.3760/cma.j.issn.0254-1424.2009.01.014
- VernacularTitle:功能性磁共振与弥散张量成像对高压氧治疗视觉通路异常疗效的评价
- Author:
Ziqian CHEN
;
Ping NI
;
Youqiang YE
;
Hui XIAO
;
Gengnian QIAN
;
Shangwen XU
;
Jingliang WANG
;
Xizhang YANG
;
Jinhua CHEN
- Publication Type:Journal Article
- Keywords:
Visual rehabilitation;
Functional magnetic resonance imaging;
Diffusion tensor imaging;
Hyperbaric oxygen therapy
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2009;31(1):36-42
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the rehabilitating effect of hyperbaric oxygen on visual pathway lesions with blood oxygen level dependent functional magnetic resonance imaging (BOLD-fMRI) and diffusion tensor imaging (DTI). Methods Sixteen patients with visual pathway lesions (the study group) and twelve healthy volunteers (the control group) were assessed using BOLD-fMRI and DTI. After hyperbaric oxygen therapy, the patients in the study group were again assessed using BOLD-fMRI and DTI. The activated regions of the BOLD-fMRI scan and the fractional anisotropy (FA) value determined from the DTI were calculated. Results Before hyperbaric oxygen treatment, there were significant differences between control and study groups in their BOLD-fMRI activated regions and the FA values of their radiation optics (P≤0.01). After hyperbaric oxygen treatment, there were no significant differences. Conclusion Combining BOLD-fMRI with DT1 could be used to evaluate the rehabilitation effect of hy-perbaric oxygen treatment in patients with visual pathway lesions.
