Incidence of acute kidney injury according to AKI Network after cardiac surgery and analysis of risk factors and outcome
10.3760/cma.j.issn.1001-7097.2009.04.004
- VernacularTitle:AKI网络定义的急性肾损伤在心脏手术后患者中的发生情况及其危险因素和预后分析
- Author:
Miaolin CHE
;
Yi LI
;
Xinyue LIANG
;
Huili DAI
;
Mingli ZHU
;
Leyi GU
;
Jiaqi QIAN
;
Zhaohui NI
;
Song XUE
;
Yucheng YAN
- Publication Type:Journal Article
- Keywords:
Kidney diseases;
Kidney insufficiency,acute;
Cardiac surgery;
Epidemiology;
Risk factors
- From:
Chinese Journal of Nephrology
2009;25(4):265-271
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the incidence, risk factors and outcome of acute kidney injury (AKI) following cardiac surgeries. Methods Clinical data of 1056 patients undergoing open heart surgery in Renji Hospital from January 2004 to June 2007 were retrospectively analyzed. Univariate and multivariate analyses were used to evaluate possible pre-,intra-, and post-operative parameters associated with AKI according to AKI Network (AKIN). Results Of the 1056 patients, 328 (31.06%) developed AKI. In-hospital mortality was 4.07% in all discharges while 11.59% in AKI patients (P<0.01). Multivariate logistic regression analysis revealed that increased age (OR=1.40), pre-operative hyperurieemia (OR=1.97), pre-operative left ventricular insufficiency (OR=2.53), combined surgery (OR=2.79), prolonged operation time (OR=1.43), post-operative circulation volume insufficiency (OR=11.08) were risk factors of AKI. Conclusions AKI is a common complication and associated with increased mortality following cardiac surgery. Increased age, pre-operative hyperuricemia, pre-operative left ventricular insufficiency, combined surgery, prolonged operation time, post-operative circulation volume insufficiency are useful in stratifying risk factors for the development of AKI.
