Treatment of acute gastroesophageal variceal bleeding with combination of endoscopic cyanoacrylate injection and endoscopic variceal ligation
10.3760/cma.j.issn.1007-5232.2009.03.004
- VernacularTitle:内镜下组织胶注射联合套扎治疗急性胃食管静脉曲张出血的临床应用
- Author:
Yanhu FENG
;
Xiaojun HUANG
;
Ziyan LIU
;
Hong FAN
;
Xiang WANG
;
Wei WANG
- Publication Type:Journal Article
- Keywords:
Esophageal and gastric varices;
Hemorrhage;
Hemostasis,Endoscopic;
Endo-scopic variceal ligation;
Tissue adhesive
- From:
Chinese Journal of Digestive Endoscopy
2009;26(3):120-123
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of endoscopic cyanoacrylate injection combined with endoscopic variceal libation (EVL) in treatment of acute gastroosophageal variceal bleeding. Methods Twenty-three patients with acute esophagogastric variceal bleeding received endoscopic cyanoacrylate injec-tion combined with EVL within 12 hours of hemostssis. Somatostatin were given intravenously at the dosage of 250 μg/h postoperatively for 72 h. The patients received follow-up endoscopy at 2 weeks and 3 months after the procedure, respectively. The variants including the rate of re-bleeding, mortality, and degree of esopha-gogastric varices were evaluated. Results Success in immediate hemostasis was achieved in all cases and a second EVL was performed in 6 patients 2 weeks later. The effective rate of variceal alleviation in gastric fun-dus was 95.65% and 91.30% in esophageal varices. No recurrent bleeding or death was observed in follow-up of 3 months. Conclusion Endoscopic eyanoaerylate injection combined with EVL is a safe and effective technique in the treatment of patients with acute gastroesophageal variceal bleeding.
