Endoscopic embolization combined with variceal ligation in the treatment of gastroesophageal variceal bleeding
10.3760/cma.j.issn.1007-5232.2009.03.006
- VernacularTitle:经内镜栓塞术联合套扎术治疗食管胃底静脉曲张出血的疗效观察
- Author:
Chengrong WU
;
Liuye HUANG
;
Yunxiang LIU
;
Jun CUI
- Publication Type:Journal Article
- Keywords:
Esophageal and gastric varices;
Embelization,theraputic;
Ligation;
Endoscopy
- From:
Chinese Journal of Digestive Endoscopy
2009;26(3):124-127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the therapeutic effect of combined endoscopic embelization and variceal ligation (EVL) for management in cirrhotic patients with gastroesophageal variceal bleeding. Meth-otis One hundred and fifty-six cases of active gastric fundal variceal bleeding combined with esophageal var-ices of over degree Ⅱ, and with other causes leading to upper digestive tract bleeding excluded, were ran-domized into therapeutic group (n = 80) and control group (n = 76). For the therapeutic group, endoscopic cyanoacrylate injection for embelization of gastric fundal varices and EVL for esophageal varices were per-formed simultaneously. For the control group, EVL was performed 2 months after embolization. Results There was no complication in beth groups. The rate of hemostasis in therapy group was 96. 3% (77/80), and that in control group was 97. 4% (74/76, P >0.05). There was significant difference between two groups, regarding the rates of early re-bleeding [6. 4% (5/78) vs 21.3% (16/75), P < 0. 05] and re-bleeding at 6 months [13.0% (9/69) vs 25. 4% (17/67), P < 0. 05]. There was no significant difference between two groups, regarding the effective rate in disappearance of gastric fundus varices (61.6% vs 59. 1%), and in that of esophageal varices (74. 0% vs 67.9%). Conclusion Endescopic embelisation of gastric fundus vaxices, combined with EVL for esophageal varices, is a safe and effective procedure for the treatment of gastroesophageal variceal bleeding, and it can reduce the rate of re- bleeding.
