The effects of low intensity pulsed ultrasound on repair of articular cartilage injury in rabbits

VernacularTitle:低强度脉冲超声对兔关节软骨损伤修复的影响
Author: Xiaolin JIA ; Wenzhi CHEN ; Baoyong SUN ; Zhibiao WANG
Publication Type:Journal Article
Keywords: Low intensity pulsed ultrasound; Cartilage; Injury; Repair
From: Chinese Journal of Physical Medicine and Rehabilitation 2009;31(5):305-307
CountryChina
Language:Chinese
Abstract: Objective To investigate the effects of low intensity pulsed ultrasound ( LIPU ) on articular car-tilage injury in rabbits. Methods Ten adult New Zealand white rabbits with bilateral, full-thickness osteochondral defects in the cartilage surfaces of intercondylar fossas were used as model. The left knees in these rabbits treated with LIPU were used as experimental group. The right knees treated with sham intervention were used as controls. All the rabbits were sacrificed at the 8th week postoperation for gross appearance grading, histological grading and semi-quan-titation of proteoglycan in the repairing tissue. Results Compared with controls, defects treated with LIPU im-proved significantly as shown by gross appearance grades, histological grades and optical density of toluidine blue at the 8th week postoperation (both P <0.05). Conclusion LIPU could accelerate repairing of articular cartilage in-jury.