Clinicopathological characters of basal-like breast carcinoma
10.3760/cma.j.issn.1006-9801.2009.04.027
- VernacularTitle:乳腺基底细胞样癌的临床病理特征
- Author:
Chang YU
;
Xinghao NI
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Carcinoma,basal cell;
Pathology,clinical
- From:
Cancer Research and Clinic
2009;21(4):282-285
- CountryChina
- Language:Chinese
-
Abstract:
Basal-like breast carcinoma is a phenotype of breast cancer which was sub-classified according to gene expression profiling criteria, associated with specific pathological features and biological behaviour. These cancer used to be more aggressive and characterized by the absent expression of ER/PR/CerbB-2(triple negative, TG) however positive for basal cytokeratins(basal CK). We present this review to show its pathological characters, clinical progression, prognosis and response to chemotherapy, and provide convenience for pathologists and surgical colleagues be more aware of this subtype.
