Unusual Histology of Eosinophilic Myenteric Ganglionitis: A Case Report.
- Author:
Hyekyung LEE
1
;
Dongwook KANG
;
Heejin KIM
;
Byungsun CHO
;
Jeho JANG
Author Information
- Publication Type:Case Report
- Keywords: Eosinophils; Ganglionitis; Pseudo-obstruction
- MeSH: CD4-Positive T-Lymphocytes; Child; Colon, Descending; Eosinophils*; Female; Ganglion Cysts*; Humans; Intestinal Pseudo-Obstruction; Middle Aged; Myenteric Plexus
- From:Journal of Pathology and Translational Medicine 2017;51(3):320-324
- CountryRepublic of Korea
- Language:English
- Abstract: Eosinophilic myenteric ganglionitis is a disorder characterized by infiltration of the Auerbach myenteric plexus by eosinophils. As a cause of chronic intestinal pseudo-obstruction (CIPO), eosinophilic myenteric ganglionitis has been rarely reported and the majority of the reported cases in the literature were children. We experienced a case of eosinophilic myenteric ganglionitis associated with CIPO in a 53-year-old female patient. Histologic examination of the resected descending colon showed moderate eosinophilic infiltrates with hypogangliosis in the myenteric plexus. Immunohistochemical study revealed increased number of CD4-positive lymphocytes and stronger but scantier glial fibillary acid protein expression in the inflamed myenteric plexus.
