Effect of low protein diet on nitrogen balance in peritoneal dialysis patients
10.3760/cma.j.issn.1001-7097.2009.06.007
- VernacularTitle:低蛋白饮食对腹膜透析患者氮平衡的影响
- Author:
Weilan SUN
;
Jiaqi QIAN
;
Zhaohui NI
;
Liou CAO
;
Qin WANG
;
Shan MOU
;
Chunhua HU
;
Yanping WAN
;
Xiaomin ZHANG
;
Qiaug YAO
- Publication Type:Journal Article
- Keywords:
Diet,protein-restricted;
Peritoneal dislysis;
Nitrogen balance;
Nutritional status
- From:
Chinese Journal of Nephrology
2009;25(6):425-429
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the influence of different dietary protein intake (DPI) on nitrogen balance and nutritional indices in peritoneal dialysis (PD) patients, and explore the minimal DPI to maintain nitrogen balance.MethodsThirty-four PD patients were randomly divided into group A, B and C with DPI as 1.2, 0.9 and 0.6 g·kg-1·d-1 respectively. All the patients admitted into our hospital and completed a 10-day assessment for nitrogen balance, as well as nutritional status including serum albumin (Alb), pre-albumin at baseline, the 7th and 10th day. ResultsThe DPI of group A, B and C was (1.18±0.05), (0.87±0.02), (0.66±0.03) g·kg-1·d-1, whose differences were significant (P<0.01). The dietary energy intake (DEI) was 129.29 (117.57-133.89), 111.71 (100.42-133.47), 146.86 (128.03-163.18) kJ·kg-1·d-1 respectively. Nitrogen balance was positive in group A, B, C [2.99 (2.15-4.72) g, 1.20(0.59-1.89) g, 0.24 (-0.87-1.27) g]. The BUN decreased at the 7th and 10th day (P<0.01) in group C. The BUN and phosphorus in group A increased, but without significant difference as compared to baseline. No significant differences of nutritional status were found among three groups throughout the trial. ConclusionMinimal DPI 0.65 g·kg-1·d-1 plus the supplement of protein loss in dialysate can maintain the nitrogen balance in peritoneal dialysis patients.
