Effect of guide-wire assisted biliary cannulation on post-ERCP pancreatitis: a meta-analysis
10.3760/cma.j.issn.1007-5232.2009.06.006
- VernacularTitle:导丝引导胆管选择性插管对ERCP术后胰腺炎影响的系统评价
- Author:
Peng WANG
;
Wei ZHANG
;
Feng LIU
;
Zhaoshen LI
- Publication Type:Journal Article
- Keywords:
Cholangiopancreatography,endoscopic retrograde;
Pancreatitis;
Guidewire
- From:
Chinese Journal of Digestive Endoscopy
2009;26(6):290-294
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effect of guide-wire assisted cannulation and traditional con-trast assisted cannulation on the occurrence post-endoscopic retrograde cholangiopancreatography(ERCP) pan-creatitis(PEP). Methods The effect of guide-wire assisted biliary cannulation on the incidence of PEP was systematically evaluated by searching for literatures on prospective randomized controlled trials(RCTs) on the Cochrane Controlled Trials Register (Issue 4, 2008), MEDLINE (1966-Oct, 2008), EMBASE (1966-Oct 2008), Science Citation Index(1966-Oct, 2008), CBMdisk(1970-Sep, 2008) and conference abstracts(2002 -2008). A meta-analysis of these clinical trials was performed. Results Seven RCTs, with a total of 2474 patients enrolled, were retrieved. Meta-analysis demonstrated a lower risk for PEP after guide-wire assisted bil-iary cannulation (RR=0.46, 95% CI 0.25-0.85, P=0.01). However, sub-category analysis showed that it was not statistically superior to contrast assisted cannulation in reduction of PEP (RR=0.66, 95% CI 0.28-1.54, P=0.33). Conclusion Guide-wire assisted biliary cannulation might be effective in preventing PEP, but further RCTs are warranted due to the limitations of trials included in this analysis.