Clinical efficacy of benadryl cream and metronidazle cream in treatment of topical corticosteroid dependent dermatitis
10.3760/cma.j.issn.1671-0290.2009.04.002
- VernacularTitle:苯海拉明霜联合甲硝唑霜综合治疗激素依赖性皮炎的疗效
- Author:
Yuqing QI
;
Guizhi ZHANG
;
Guanglian GUO
;
Hong JIANG
;
Quanzhong LIU
- Publication Type:Journal Article
- Keywords:
Benadryl cream;
Metronidazle cream;
Topical corticosteroid dependent dermatitis
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2009;15(4):220-222
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the clinical efficacy and safety of 1% benadryl and 3 % metronidazle cream in the treatment of topical corticosteroid dependent dermatitis. Methods The study was conducted in a single-blind way. The 86 patients were divided into 3 groups: 1% benadryl and 3 %metronidazle cream (group A), loratadine (group B) and gluco-corticoids (group C). All preparations were applied twice daily for 8 weeks. Study visits took place at baseline and weeks 2, 4 and 8. Results The clinical response rate in the groups A, B and C was 86.20%, 73.33%, and 66.67%, respectively; the clinical response rate in group A was significantly higher than that in groups B and C (P<0.05). Conclusions 1% benadryl and 3 % metronidazle cream are effective and safe in the treatment of topical torticosteroid dependent dermatitis.