Prognostic analysis of patients with cerebral glioma treated with radiotherapy
10.3760/cma.j.issn.1006-9801.2009.06.013
- VernacularTitle:脑胶质瘤放射治疗的预后因素分析
- Author:
Yanxia LI
;
Shengmin LAN
- Publication Type:Journal Article
- Keywords:
Brain neoplasms;
Glioma;
Radiotherapy,computer-assisted;
Prognosis
- From:
Cancer Research and Clinic
2009;21(6):399-402
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate and analyse the prognostic factors of cerebral glioma treated with radiotherapy. Methods Records of 162 patients with cerebral glioma. Cox model was used for univariate and multivariate analysis. Results Mean follow- up time was 30 months, 14 patients relapsed, and 45 patients died. Univariate analysis showed that histologic grade, histologic type, Karnofsky performance state before radiotherapy, extent of resection, and age were significant predictors in association with overall survival rate of patients with glioma. Multivariate analysis showed that histologic grade, histologic type, age, Kamofsky before radiotherapy, extent of resection,and radiotherapy technology were independent prognostic factors of glioma. Conclusion Low grade, AC and OD, age≤40 years, Kamofsky >80 before radiotherapy, and total resection axe independent factors for predicting better survival of glioma patients.
