Clinical efficacy and safety of Kecuo Yingtong gel in treatment of acne vulgaris with a detailed staging regimen

VernacularTitle:克痤隐酮凝胶分阶段细化用药治疗寻常痤疮
Author: Heng CHEN ; Huoda ZHANG ; Hui YU ; Langfeng XU
Publication Type:Journal Article
Keywords: Kecuo yingtong gel; Acne
From: Chinese Journal of Medical Aesthetics and Cosmetology 2009;15(4):223-225
CountryChina
Language:Chinese
Abstract: Objective To evaluate the clinical efficacy and safety of Kecuo Yingtong gel with detailed treatment regimen for ache vulgaris by phase. Methods Sixty patients with acne vulgaris of mild to the severity were randomized to receive either detail by phase group (A) or conventional group (B). Group A was treated with Kecuo Yingtong gel topically 1 to 4 times daily according to the severity of the disease. Clinical responses were recorded and photographed weekly in group A, and treatment regimens were adjusted accordingly. Group B only was treated with Kecuo Yingtong gel 2 times daily for 6 to 8 weeks. Results It was shown that cure rates were 66.7% and 36.7% in the groups A and B, respectively. There was no statistical difference between the 2 groups (P<0.05). Only few patients had stimulating symptoms, and severe adverse effects had not been observed. However, incidence of the side effects was higher in group A than group B. Conclusions Kecuo Yingtong gel has been proved to have an excellent response with detailed treatment by phase. Reasonably increasing the daily dosage could improve the cure rates. The cutaneous tolerability of the drug is generally good.