A novel base-quenched probe technique for detecting single-nucleotide polymorphisms
10.3760/cma.j.issn.1009-9158.2009.09.025
- VernacularTitle:单核苷酸多态性的碱基淬灭探针技术检测方法的建立
- Author:
Jun ZHANG
;
Guanghua LUO
;
Lu ZHENG
;
Xiaoying ZHANG
;
Ning XU
- Publication Type:Journal Article
- Keywords:
Polymorphism;
single nucleotide;
Genotype;
Nucleic acid probes
- From:
Chinese Journal of Laboratory Medicine
2009;32(9):1064-1068
- CountryChina
- Language:Chinese
-
Abstract:
ncing analysis validated that all four-type base-quenched probes could provide unbiased genotyping results ( Kappa =1, P=0.00), although. Conclusion This method is simple, economic and suitable for large-scale genotyping studies.
