The effects of transfection of CXCL10 gene into breast cancer cell line MCF-7 on expression of tumor related genes
10.3760/cma.j.issn.1009-9158.2009.09.024
- VernacularTitle:CXCL10基因对乳腺癌细胞株MCF-7肿瘤相关基因表达的影响
- Author:
Bo SHEN
;
Ying FU
;
Wei XU
;
Sufei YU
;
Min ZHU
;
Zhefeng MENG
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Cell line;
tumor;
Chemopkine CXCL10;
Gene expression
- From:
Chinese Journal of Laboratory Medicine
2009;32(9):1059-1063
- CountryChina
- Language:Chinese
-
Abstract:
s were 0.573±0.016, 0.707±0.008 and 0.711±0.013). Conclusions CXCL10 can express stablely in MCF-7 cell lines, which resulted in down-regulation of expression of VEGF and STAT3 gene. CXCL10 played an important role in anti-tumor effect.
