STAT3 and tumor therapeutic target
10.3760/cma.j.issn.1006-9801.2009.11.029
- VernacularTitle:STAT3与肿瘤的靶向治疗
- Author:
Jiongyi WANG
;
Bin JIANG
- Publication Type:Journal Article
- Keywords:
STAT3 transcription factor;
Neoplasms;
Therapy
- From:
Cancer Research and Clinic
2009;21(11):789-792
- CountryChina
- Language:Chinese
-
Abstract:
STAT3, as a member of signal transducers and activators of transcription (STATs) family,which has been recognized as one of the common pathways in cancer cells. STAT3 has been found in many tumor cells that are critical to cell survival, cell proliferation, invasion, angiogenesis and immune evasion.Thus, STAT3 signaling pathway may be a potential therapeutic target for tumor metastasis.
