Endoscopic submucosal dissection for early gastric cancer
10.3760/cma.j.issn.0254-1432.2009.10.008
- VernacularTitle:内镜黏膜下剥离术在早期胃癌治疗中的应用
- Author:
Xingang SHI
;
Zhaoshen LI
;
Danfeng XU
;
Jie CHEN
;
Zhendong JIN
;
Xianbao ZHAN
;
Duowu ZOU
;
Guoming XU
- Publication Type:Journal Article
- Keywords:
Stomach neoplagms;
Endoscopy,digestive system;
Reproducibility of results
- From:
Chinese Journal of Digestion
2009;29(10):670-673
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of endoscopic submucosal dissection (ESD)in treatment of patients with early gastric cancer(EGC).Methods A total of 4 3 consecutive patients with EGC were treated with ESD at Changhai Hospital from July 2007 to July 2008.The data referred to one-piece resection,histologically complete resection,operation time,complications,the post-ESD ulcer-healing and local recurrance were retrospectively analyzed.ResultsEn bloc resection was achieved in 97.7 0A(4 2/43)lesions in one-piece resection.The histologically complete resection rate was 95.3%(41/43).Only one patient had acute minor bleeding during the ESD procedure(2.3%,1/43)and one patient had delayed bleeding(2.3%,1/43).Post-ESD epigastric pain was found in 2 2 patients(51.2%).There was no complications such as acute major bleeding,perforation,requiring surgical treatment and death.The median operation time was 60.4 miutes.The post-ESD ulcer-healing was achieved in 100%(42/42)8 weeks after esomeprazole treatment.During follow-uP of 10.3 months(ranged from 8 to 1 8 months),no residual or local recurrence of EGC was seen.Conclusion ESD has the advantages of increasing one-piece resection and histologically curative resection rates.It is a safe and effective procedure in treatment of EGC.
