Cerebral perfusion semi-quantitative imaging for assessing the treatment of delayed encephalopathy from carbon monoxide poisoning

VernacularTitle:脑血流灌注半定量法显像评价高压氧联合药物治疗一氧化碳中毒迟发性脑病疗效
Author: Bing XIONG ; You ZHOU ; Yali CAI ; Hongbiao LIU ; Zhongquan TANG ; Da SUN ; Xing XU ; Wenming LIU
Publication Type:Journal Article
Keywords: Hvperbaric oxygen; Encephalopathy; Carbon monoxide poisoning; Single photon emission computed tomography
From: Chinese Journal of Physical Medicine and Rehabilitation 2009;31(11):756-759
CountryChina
Language:Chinese
Abstract: Objective To evaluate the effects of hyperbaric oxygen (HBO) combined with drug therapy on patients with delayed encephalopathy caused by carbon monoxide poisoning ( COP). Methods Twenty to forty sessions of HBO therapy were used to treat 34 COP patients. Assessment relied on 99mTc-ethyl cysteinate dimer (~(99m)Tc-ECD) single photon emission computed tomography (SPECT) imaging of cerebral perfusion before and after treatment. Results After HBO therapy, cerebral perfusion in the COP patients improved significantly. There was a significant difference of the SPECT images before and after treatment. Conclusions SPECT imaging of cerebral perfusion can play an important role in the diagnosis of delayed encephalopathy caused by carbon monoxide poisoning, and it can be used for the therapeutic surveillance of HBO treatment.