Effects of pulsed electromagnetic fields on mechanical allodynia after acute skeletal muscle contusion in rats
10.3760/cma.j.issn.0254-1424.2010.01.003
- VernacularTitle:脉冲电磁场对大鼠骨骼肌急性挫伤后触诱发痛的影响
- Author:
Jing WANG
;
Changjie ZHANG
;
Xudong GU
;
Yunhai YAO
- Publication Type:Journal Article
- Keywords:
Skeletal muscle;
Contusion;
Pain;
Pulsed electromagnetic fields
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2010;32(1):6-8
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of pulsed electromagnetic fields (PEMFs) on behavior and mechanical paw withdrawal thresholds (MPWTs) after acute skeletal muscle contusion (ASMC) in rats, and to in-vestigate the application of PEMFs in rats with ASMC during the early stage. Methods Forty-two Sprague-Dawley rats were randomly divided into a PEMF group (P group) , control group (C group) and blank control group ( BC group). ASMC models were set up in groups P and C, and no intervention was applied in the BC group. A PEMF was administered to animals in the P group immediately after the ASMC was inflicted. The behavior of the rats in each group was then observed. The MPWT of each rat was tested 2 days before and 0, 12, and 18 hours after the ASMC was inflicted). Results In the P and C groups, MPWT of the left hind paw at the 12th and 18th hour after ASMC was significantly lower than the baseline pain threshold 2 days before the ASMC. At 18 hours, the MPWT was signifi-cantly higher than at 12 hours in the P group. MPWT at 12 hours in the P group and at both 12 and 18 hours in the C group were significantly lower than in the BC group. MPWT in the P group at 18 hours was significantly higher than in the C group. Conclusions The behavior of rats treated with PEMF immediately after ASMC was improved, and their pain threshold was still elevated 18 hours later.
