Predictive value of superficial depression in estimation of histology and invasive depth of colorectal neoplasia
10.3760/cma.j.issn.1007-5232.2010.02.002
- VernacularTitle:结直肠肿瘤表面凹陷形态对判断病变性质及浸润深度的作用
- Author:
Xiaobo LI
;
Huimin CHEN
;
Yunjie GAO
;
Xiaoyu CHEN
;
Zhizheng GE
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Endoscopic mucosal resection;
Hyperplasia;
Chromoendoscopy
- From:
Chinese Journal of Digestive Endoscopy
2010;27(2):60-63
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the predictive value of morphology of superficial depression in estimation of histology and invasive depth in colorectal neoplasia by using magnifying chromo-endoscopy.Methods Flat or depressed and sessile eolorectal lesions which were indicated for endoscopic mucosal resection (EMR) were consecutively collected. Depressed lesions were classified into type 1 (star-like) and type 2 (round) according to the morphology of depressive areas in the colorectal neoplasia with magnifying ehromoendoscopy. The relationship between morphologic classification with histology and invasive depth was studied with reference to pathological diagnosis after EMR. Results Ninety lesions including 25 sessile and 65 flat were resected with EMR. Lesions with central depression (54. 4%,49/90) were more likely to have high-grade dysplasia (HGD) or cancer than those without ( 51.0% vs. 17. 1%,P＜0. 001 ). Depressive lesions of type 2 were more susceptible to have HGD or cancer than those of type 1 (89. 5% vs. 26. 7%,P＜0. 001 ). The overall accuracy of depression morphology for distinction between lesions of superficial submueosal (m-sm1) and deep submucosal (sm2-sm3) invasion was 83. 7% (41/49). Conclusion The morphology of superficial depression on colorectal neoplasia is highly correlated with the histology and invasive depth,which facilitates the EMR treatment.
