Age related reference value for reticulocyte hemoglobin equivalent among children aged one to thirteen years
- VernacularTitle:1～13岁健康儿童年龄相关的网织红细胞血红蛋白含量参考范围的测定
- Author:
Yuefang WANG
;
Hui YANG
;
Xia WANG
;
Juan LI
;
Lan CHEN
;
Hong WANG
;
Qi CHEN
;
Yongmei JIANG
- Publication Type:Journal Article
- Keywords:
Erythrocyte indices;
Reference values;
Age factors;
Child
- From:
Chinese Journal of Laboratory Medicine
2008;31(7):767-770
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish age related reference value for the new reticulocyte hemoglobin equivalent (RET-He) parameter in healthy children aged one to thirteen years. Methods Reticulocyte hemoglobin equivalent was measured by Sysmex XE-2100 after completing daily internal quality control in 424 healthy children and the outlying observations was handled afterward, Age related reference value anddistribution of RET-He level were described as the 2.5th and 97.5th centiles, and the equation regardingage related reference value was established through curve fitting methods. Results After grouping accordingto sex, the medians of boys and girls in RET-He were 31.30 pg,31.80 pg. Non-parametric test showed therewas no differences between the boys and girls. When the data from two group was integrated together, thefitted equations of RET-He were: P2.5 =-0.008X3+0.125X2 - 0.178X+26.456; P97.5= 0.021X2-0.184X+34.670(X refers to age) ; R2 were 0.85 and 0.90,respectively(P <0.05). There was statisticallysignificance for the above equations. Conclusions The reference value of RET-He in healthy children isdifferent from those in adult. The equations can be used to produce age related reference value. It could beuseful for anemia diagnosis, differential diagnosis and hematopoiesis screening at early stage.
