Clinical analysis of nutcracker syndrome complicated with IgA nephropathy
10.3760/cma.j.issn.1001-7097.2010.01.008
- VernacularTitle:胡桃夹综合征并发IgA肾病临床分析
- Author:
Yaomin WANG
;
Xiaohui ZHANG
;
Qiang HE
;
Jianyong WU
;
Jianghua CHEN
- Publication Type:Journal Article
- Keywords:
Glomerolonephritis,IgA;
Hematuria;
Nutcracker syndrome;
Ultrasonography;
Magnetic resonance angiography
- From:
Chinese Journal of Nephrology
2010;26(1):25-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective To elucidate the clinical features of nutcracker syndrome complicated with IgA nephropathy (IgAN) and to increase its level of diagnosis and treatment. Methods Clinical data of 14 cases of nutcracker syndrome complicated with IgA nephropathy (patient group) and 36 cases of nutcracker syndrome (control group) were analyzed retrospectively. Nutcracker syndrome was diagnosed by ultrasonography and magnetic resonance angiography (MRA) and IgAN by renal biopsy. Differences of clinical data and images in two groups were analyzed. Results Gender, age and blood pressure of two groups were not significantly different. Higher Scr level [(81.2±21.3) μmol/L vs (61.2±11.8) μmol/L, P<0.01], more severe proteinuria [(1.1 ± 0.6) g/d vs (0.3±0.2) g/d, P<0.01] and hematuria (2.3±0.9 vs 1.5±1.3, P<0.05) in patient group were found. Differences of ultrasonography and MRA in two groups were not significant. Conclusion Renal biopsy should be considered in cases of nutcracker syndrome with persistence of proteinuria, hematuria or abnormal morphology of urinary red blood cell.