Management for neonatal pulmonary atresia with intact ventricular septum
10.3760/cma.j.issn.1007-9408.2010.03.009
- VernacularTitle:新生儿室间隔完整型肺动脉闭锁的治疗
- Author:
Jingjing HUANG
;
Yaping MI
;
Bing JIA
;
Zhanggen CHEN
;
Yonghao GUI
- Publication Type:Journal Article
- Keywords:
Pulmonary atresia;
Cardiac surgical procedures;
Heart defects,congenital;
Infant,newborn
- From:
Chinese Journal of Perinatal Medicine
2010;13(3):213-216
- CountryChina
- Language:Chinese
-
Abstract:
Objective A retrospective study was undertaken to evaluate the outcomes of the newborns with pulmonary atresia with intact ventricular septum(PAIVS),in order to delineate strategies for the optimal management of PAIVS. Methods From July 2003 to July 2008,17 neonates with PAIVS underwent surgical treatment.The mean age at operation was(1 5.6±8.6)d and the mean weight was(3.54±0.44)kg.Initial surgical treatment included:Blalock-Taussig shunt (BT shunt)in 2 cases,closed pulmonary valvotomy and BT shunt in 1 case,right ventricular outlet tract reconstruction(RVOTR)in 2 cases,RVOTR and BT shunt in 11 cases. Results The mean duration of mechanical ventilation and intensive care unit stay were(35.5±35.1)h and(8.7±5.9)d,respectively.Two early deaths were reported inside the hospital(2/17,11.8%).Multivariable analysis demonstrated that mechanical ventilation before surgery was the risk factor for in-hospital mortality(r=1.02,P<0.01).The rest 15 cases were followed up with the average time of 19 months(2 months to 5 years)and no death was reported. Conclusions Neonates with PAIVS should be operated early.Individualized treatment strategy and regular follow-up are helpful to achieve better short-term outcome.
