Survival analysis of 204 patients with pancreatic cancer

VernacularTitle:204例胰腺癌患者生存分析
Author: Dexiang ZHANG ; Suxu YUAN ; Yuedi DAI
Publication Type:Journal Article
Keywords: Pancreatic neoplasms; Disease-free survival; Retrospective studies
From: Chinese Journal of Digestion 2010;30(4):236-240
CountryChina
Language:Chinese
Abstract: Objective To investigate the impacts of clinical features, blood and biochemical parameters on survival of patients with pancreatic cancer. Methods Two hundred and four patients with pathologically performed pancreatic cancer were retrospectively analyzed. All patients were followed-up by means of phone. Results The survival rate of 204 patients with pancreatic cancer was 32.8% at 1-year, 13.7% at 3-year and 2.9% at 5-year, with medium survival time of 6.4 months. Univariate examination showed that the long survival time was found in patients with radical or palliate operation in comparison with those without (P<0.01). The factors that impacted on the survival times were high tumor marker, .high serum creatinine, high white blood cells, low hemoglobin and low albumin (P<0.01). Whereas the patients with high levels of ALT and AST had long survival time (P(0.05). COX regression analysis revealed that those with advanced stage, low albumin and high creatinine had short survival time(P<0.05). Conclusions Surgery, tumor stage, tumor marker, hemoglobin, white blood cell, albumin and creatinine are independent prognostic factors.