Clinical analysis of 18 cases with solitary bone plasmacytoma

VernacularTitle:骨孤立性浆细胞瘤18例临床分析
Author: Zhi GUO ; Feng CHEN ; Dezhang MA ; Xuepeng HE ; Huiren CHEN ; Yukui ZHANG ; Bichuan HU ; Yan JI ; Rong QU
Publication Type:Journal Article
Keywords: Solitary bone plasmacytomas; Clinical analysis; Therapy; Follow-up; Retrospective studies
From: Cancer Research and Clinic 2010;22(4):222-224
CountryChina
Language:Chinese
Abstract: Objective To improve the diagnosis level of solitary bone plasmacytoma (SBP) through analysing the clinical characteristics and therapy of this disease. Methods The clinical data of 18 cases were retrospectively analysis since 1999 in five hospitals, the clinical characteristics and therapeutic effect was summarized. Results The average age of 18 cases is 54.2 year (35-78), male were 1.6 times than female. 8 of 10 patients survived for 1-10 year after chemoradiotherapy, 2 of them progressed to multiple myeloma (MM)and died. 5 of 8 patients survived after only chemotherapy or radiotherapy. There were 11 cases of all patients in continue complete remission (CCS), the average CCS time was 47.3 months. Conclusion SBP is a type low-grade malignant tumor. Chemotherapy and radiotherapy is the main therapy. The patients can gain satisfactory prognosis with chemoradiotherapy, part of them can progress to MM.