Evaluation of 3.0T 1H-MR spectroscopy imaging in the diagnosis and grading of gliomas
10.3760/cma.j.issn.1006-9801.2010.04.011
- VernacularTitle:多体素1H磁共振波谱在脑胶质瘤诊断及分级中的应用研究
- Author:
Yanbing WANG
;
Tong ZHANG
;
Rui XU
;
Guohua WANG
- Publication Type:Journal Article
- Keywords:
Neoplasms,neuroepithelial;
Magnetic resonance spectroscopy;
Diagnosis,differential
- From:
Cancer Research and Clinic
2010;22(4):250-254
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value in MR spectrum of diagnosis and grading of gliomas.Methods 36 cases of patient with gliomas who confirmed by histopathologic findings or clinical follow-up were collected. Using a GE Signa EXCITE HD 3.0T super conduct MR unit, all the cases of patients were performed conventional MR scan and multi-voxel with 2-D multi-voxel PRESS 144 ms. Functool software was used for post-processing of spectrum. The ratios of NAA/Cr, NAA/Cho, Cho/Cr were measured in the solid part of masses, circum of tumors and contralateral parenchyma respectively. The result was processed by the statistical method. Results The statistical analysis was exacted by SAS 8.2 software. In the solid part of masses, there were significant differences between low-grade gliomas and high-grade gliomas in the ratios of Cho/Cr, Cho/NAA、NAA/Cr and MI (P ＜0.05), but in peritumoral edema, there were significant differences in the ratios of Cho/Cr, NAA/Cr (P ＜0.05), and no significant differences in the ratios of MI (P ＜0.05).Conclusion 1H-MRS is very important and useful in the evaluation of gliomas. It has made it possible to exactly evaluate the grade of gliomas combined with other imagings.
