Clinical effective durations after intracutaneous injection of a medical collagenous production
10.3760/cma.j.issn.1671-0290.2010.03.006
- VernacularTitle:注射医用胶原显效持续时间的观察
- Author:
Yan JIN
;
Haibo WANG
;
Yongmei CHEN
;
Wenzhi LI
- Publication Type:Journal Article
- Keywords:
Cosmetics techniques;
Wrinkles;
Collagen
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2010;16(3):161-163
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical effective durations of a medical injected collagenous products, a high-purity medical injectable collagen filling agents extracted from bovine leather (Fumeida Produced by Changchun Botai Pharmaceutical Biotechnology Co, Ltd). Methods 30 subjects (60 sides) with moderate to severe nasolabial fold wrinkles were selected to perform a clinical observation, in which 49 sides with moderate and 11 sides with severe labial fold wrinkles, and the average age of subjects were (41. 80 ± 8. 03) years. 1 ml of medical collagen was injected into the subjects wrinkle on each side by surgeons. The follow-up was made immediately, 7, 30, 90, 150 and 360 days after injection. The photograph was taken, and the image data and the validity were analyzed. Results The follow-up rate of immediate to 150 days after injection was 100 %, and 93. 3 % after 350 days. At the each follow-up points, the total effective rates were as follows: 100. 0 %, 100. 0 % , 96. 7 %, 90. 0 %, 83. 3 % and 44. 6 % .respectively. There were dry lips with herpes simplex in two cases of subjects at 7 d and 90 d after injection, no redness, induration, exudate, ulceration or other abnormal performance on collagen injection zone in the other subjects at each follow-up time point. Conclusion In this study, there is the longer clinical effective duration of injected collagen used in filling wrinkles with satisfactory results.
