The relationship between leptin and malignant tumor formation
10.3760/cma.j.issn.1006-9801.2010.03.021
- VernacularTitle:瘦素与恶性肿瘤形成的关系
- Author:
Xiaoli XIAO
;
Demin PU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Leptin;
Leptin-recepter;
Neovascularization,pathologic;
Matrix metalloproteinases;
Apoptosis
- From:
Cancer Research and Clinic
2010;22(3):208-211
- CountryChina
- Language:Chinese
-
Abstract:
Leptin as a polypeptide has a wide range of biologic effects, which can regulate appetite and energy metabolism common with leptin receptor. Recent studies found that leptin was related with tumor formation and development, which contribute to tumor progression by increasing angiogenesis, stimulates cell proliferation, adhesion and invasion through multiple channels.
